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Authors
Affiliations
1 Diabetes & Endocare Clinic, Berhampur, IN
2 Dept of Endocrinology, CMC, Vellore, IN
3 Dr Modi’s Clinic, Hyderabad, IN
4 SSMO at Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, IN
Source
The Indian Practitioner, Vol 68, No 11 (2015), Pagination: 37-45
Abstract
Type 2 diabetes mellitus (T2DM) and obesity have become common accompaniments with resultant increase in morbidity and mortality. Obesity by its causation of insulin resistance leads to increased risk of T2DM. Dietary modification and lifestyle changes fail to maintain weight loss and glycaemic control in the longer term. Bariatric surgery by virtue of substantial and sustained reduction of weight is increasingly proving to be an effective therapy to deal with the rising trend of complications arising out of these dual disorders. Bariatric surgeries result in higher rates of short and long-term diabetes remission. Improvement in insulin action, betacell function and hormonal interplay in the entero-insular axis seem to play major role. Our current article will provide an overview of effectiveness of bariatric surgeries and the proposed mechanisms.
